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In the DURATION-8 trial, patients treated with exenatide ER plus dapagliflozin achieved nearly double the weight reduction observed with each monotherapy, with numerically larger effects in individuals with higher baseline BMI
It confirmed the tanning effect, but also multiple unexpected side effects that led to the development bifurcation (PT-141 for sexual function, Afamelanotide for cutaneous indications)
Graabk T, Nguyen NT, Srensen MS, Lundby C
International agencies have warned consumers against buying products marketed under the name melanotan
